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Condition

Insulin Resistance

Insulin resistance precedes type 2 diabetes. Learn how GLP-1 medications and lifestyle support improve metabolic health.

Insulin resistance is a metabolic condition where the body's cells respond less effectively to insulin, raising blood sugar over time. It is the precursor to type 2 diabetes. GLP-1 medications like semaglutide improve insulin sensitivity, support weight loss, and reduce diabetes risk when combined with diet and exercise.

Education

Understanding the condition

When cells stop responding well to insulin, your pancreas compensates by producing more — a state called hyperinsulinemia. Over years this drives weight gain, energy crashes, and eventually type 2 diabetes. GLP-1 therapy directly improves insulin sensitivity while supporting weight loss.

Common signs

  • Energy crashes after meals
  • Stubborn abdominal weight
  • Sugar cravings
  • Skin tags or dark patches (acanthosis nigricans)
  • Elevated fasting insulin or HOMA-IR

Risk factors

  • Family history of type 2 diabetes
  • PCOS
  • Sedentary lifestyle
  • Excess refined carbohydrate intake
  • Visceral adiposity

This page is educational and is not a diagnosis. A licensed provider evaluates your individual health history before any treatment decision.

Treatment options

Protocols that address it

Prescribed only if a licensed provider determines treatment is appropriate for you.

Questions

Insulin Resistance, answered.

More questions answered in the full FAQ.

Insulin Resistance, addressed.

Share your health history online. A licensed provider will determine whether treatment is appropriate for you.

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